TY - JOUR T1 - BEnefits and risks of aspirin use AU - Lund JL, Stürmer T, Toft-Sørensen H Y1 - 2012/09/19 N1 - 10.1001/2012.jama.10720 JO - JAMA SP - 1088 EP - 1089 VL - 308 IS - 11 N2 - To the Editor: Ms De Berardis and colleagues1 reported that the use of low-dose aspirin was associated with a 55% increase in risk of major bleeding, consistent with existing evidence,2 but the incidence rates in both aspirin users and those not using aspirin were substantially higher than previously reported.2 Although it is plausible that the rates are higher in unselected patients, flaws in the study's methods may have resulted in an overestimation of bleeding rates. SN - 0098-7484 M3 - doi: 10.1001/2012.jama.10720 UR - http://dx.doi.org/10.1001/2012.jama.10720 ER -