TY  - JOUR
T1  - BEnefits and risks of aspirin use
AU  - DiNicolantonio JJ, O’Keefe JH, Lavie CJ
Y1  - 2012/09/19
N1  - 10.1001/2012.jama.10717
JO  - JAMA
SP  - 1088
EP  - 1089
VL  - 308
IS  - 11
N2  - 
To the Editor: Ms De Berardis and colleagues1 stated, “The benefit of aspirin for the primary prevention of cardiovascular events is relatively small for individuals with and without diabetes. This benefit could easily be offset by the risk of hemorrhage.” We disagree with their conclusion that aspirin use is associated with harm (major gastrointestinal or cerebral bleeding episodes) because they conducted a population-based cohort study, not a randomized controlled trial (RCT), and thus cannot prove causation.1

SN  - 0098-7484
M3  - doi: 10.1001/2012.jama.10717
UR  - http://dx.doi.org/10.1001/2012.jama.10717
ER  -