TY - JOUR T1 - PAthways to bone metastasis AU - Hampton T Y1 - 2012/09/05 N1 - 10.1001/2012.jama.10870 JO - JAMA SP - 853 EP - 853 VL - 308 IS - 9 N2 - By comparing primary and metastatic tumor cells in a mouse model of spontaneous bone metastasis, a team of investigators from Australia, Belgium, England, and the United States found that many genes that are suppressed in bone metastases are targets of the interferon regulatory factor Irf7, which promotes a robust immune response. SN - 0098-7484 M3 - doi: 10.1001/2012.jama.10870 UR - http://dx.doi.org/10.1001/2012.jama.10870 ER -