TY  - JOUR
T1  - EGg allergy treatment
AU  - Kuehn BM
Y1  - 2012/08/22
N1  - 10.1001/2012.jama.10160
JO  - JAMA
SP  - 753
EP  - 753
VL  - 308
IS  - 8
N2  - 
A team of researchers conducted a clinical trial of 55 children aged 5 to 11 years with an egg allergy to determine whether exposure to tiny amounts of egg over time might desensitize children to egg. This strategy has previously shown promise for individuals with peanut allergy (Burkes AW et al. N Engl J Med. doi: 10.1056/NEJMoa1200435 [published online July 19, 2012]). The children were randomized to receive a placebo or an oral dose of powdered egg white daily. At 10 months, more than half of the treated children were desensitized, and at 22 months, 75% of the treated children were desensitized. None of the children receiving placebo were desensitized. After 22 months, desensitized children discontinued therapy and avoided egg for 4 to 6 weeks; of these individuals, 28% remained desensitized when retested.

SN  - 0098-7484
M3  - doi: 10.1001/2012.jama.10160
UR  - http://dx.doi.org/10.1001/2012.jama.10160
ER  -