TY - JOUR T1 - USe of statins in healthy men—reply AU - Redberg RF, Katz MH Y1 - 2012/08/15 N1 - 10.1001/jama.2012.8732 JO - JAMA SP - 666 EP - 667 VL - 308 IS - 7 N2 - Dr Beckman suggests that Ray et al1 should have used a fixed-effects model instead of a random-effects model. However, given the different types of studies involved, it is more appropriate to assume that the true effect varies between studies and perform a random-effects model. Furthermore, even with the fixed-effect model, the result is not significant (ie, the upper confidence limit includes 1.00) or no benefit from statins. SN - 0098-7484 M3 - doi: 10.1001/jama.2012.8732 UR - http://dx.doi.org/10.1001/jama.2012.8732 ER -