TY  - JOUR
T1  - CHronic stress and depression
AU  - Hampton T
Y1  - 2012/08/01
N1  - 10.1001/jama.2012.9458
JO  - JAMA
SP  - 444
EP  - 444
VL  - 308
IS  - 5
N2  - 
Previous studies have linked decreased plasticity (the ability of brain cells to reorganize in response to new events) in the brain's hippocampus to chronic depression. In this study, investigators from the United States and South Korea found that chronic unpredictable stress decreases hippocampal expression of a gene that regulates neuronal plasticity by producing a protein called neuritin and that antidepressant treatment reverses this effect.

SN  - 0098-7484
M3  - doi: 10.1001/jama.2012.9458
UR  - http://dx.doi.org/10.1001/jama.2012.9458
ER  -