TY - JOUR T1 - PReexposure prophylaxis for hiv infection AU - Steinbrook R Y1 - 2012/09/05 N1 - 10.1001/jama.2012.9885 JO - JAMA SP - 865 EP - 866 VL - 308 IS - 9 N2 - On July 16, 2012, the US Food and Drug Administration (FDA) approved a daily oral antiretroviral drug to reduce the risk of sexual acquisition of human immunodeficiency virus (HIV) infection by uninfected adults.1- 2 Emtricitabine/tenofovir disoproxil fumarate (marketed by Gilead as Truvada) contains 2 nucleoside analogue HIV-1 reverse transcriptase inhibitors. Initially approved in 2004 to treat HIV infection in combination with other antiretroviral medications in people 12 years of age and older, emtricitabine/tenofovir costs about $13 900 a year in the United States for a year of treatment. SN - 0098-7484 M3 - doi: 10.1001/jama.2012.9885 UR - http://dx.doi.org/10.1001/jama.2012.9885 ER -