TY - JOUR T1 - ARrhythmia management in myotonic dystrophy type 1 AU - Groh WJ, Bhakta D Y1 - 2012/07/25 N1 - 10.1001/jama.2012.6807 JO - JAMA SP - 337 EP - 338 VL - 308 IS - 4 N2 - To the Editor: Dr Wahbi and colleagues1 concluded that sudden death mortality was improved in patients with myotonic dystrophy type 1 (DM1) and moderate conduction abnormalities on electrocardiogram who underwent an invasive strategy consisting of an electrophysiological study followed by prophylactic pacing if the HV interval exceeded 70 milliseconds. In our opinion, there are uncertainties in how the retrospective observational trial was conducted and reported that limit the ability to determine if their invasive strategy was associated with a survival advantage. SN - 0098-7484 M3 - doi: 10.1001/jama.2012.6807 UR - http://dx.doi.org/10.1001/jama.2012.6807 ER -