TY  - JOUR
T1  - HIv and liver disease
AU  - Monson T
Y1  - 2012/07/25
N1  - 10.1001/jama.308.4.410-b
JO  - JAMA
SP  - 410
EP  - 411
VL  - 308
IS  - 4
N2  - 
Chapter 1 sketches current trends of the HIV epidemic, although the most recent data are from 2010. In the chapter on liver disease in HIV, Butt addresses well-recognized factors of drug-related liver injury: ethanol use and coinfection with hepatitis B virus (HBV) and hepatitis C virus (HCV). It is generally less appreciated that nonalcoholic fatty liver disease is relatively common, with magnetic resonance imaging and computed tomography studies reporting a 37% to 42% rate of steatosis among patients with HIV alone, increasing to 67% to 69% among those coinfected with HBV or HCV (pp 10-11). The degree of steatosis correlates with the risk of fibrosis. A special notation is also made of “nodular regenerative hyperplasia,” a newer entity perhaps 3 times more common in patients with vs without HIV.

SN  - 0098-7484
M3  - doi: 10.1001/jama.308.4.410-b
UR  - http://dx.doi.org/10.1001/jama.308.4.410-b
ER  -