TY  - JOUR
T1  - REtinal detachment and fluoroquinolones
AU  - Nowroozzadeh MH
Y1  - 2012/07/18
N1  - 10.1001/jama.2012.6630
JO  - JAMA
SP  - 233
EP  - 233
VL  - 308
IS  - 3
N2  - 
First, the authors stated that “The risk of retinal detachment from our study was only elevated among current users but not among recent or past users, indicating an acute adverse event.”1 Table 3 of the article showed that the numbers of patients with retinal detachment and fluoroquinolone use were 145, 12, and 288 in current, recent, and past users, respectively. Although the sample sizes in the current and past users subgroups seem adequate, enrollment of only 12 patients in the recent use subgroup raises concern about the power of the study to detect an association. Providing information about the power of the study to detect statistically significant associations would be beneficial.

SN  - 0098-7484
M3  - doi: 10.1001/jama.2012.6630
UR  - http://dx.doi.org/10.1001/jama.2012.6630
ER  -