TY - JOUR T1 - REsearch yields new insights into mechanisms and treatment of pain AU - Friedrich MJ Y1 - 2012/01/18 N1 - 10.1001/jama.2011.1972 JO - JAMA SP - 239 EP - 241 VL - 307 IS - 3 N2 - In neither type of pain is the pathogenesis completely understood, and a comprehensive picture of the mechanisms underlying these pain states, as well as the long-term consequences of injury, is needed to develop more effective pain therapies. While the drugs available to treat chronic pain are occasionally effective, rarely are they able to alleviate pain completely, said Allan Basbaum, PhD, of the University of California at San Francisco. “Inevitably, they stop working for reasons we don't understand, or the adverse side effect profile of the treatment makes it impossible for the patient to tolerate it,” he said. SN - 0098-7484 M3 - doi: 10.1001/jama.2011.1972 UR - http://dx.doi.org/10.1001/jama.2011.1972 ER -