TY  - JOUR
T1  - SEx differences in presentation of myocardial infarction—reply
AU  - Canto JG, Goldberg RJ, Kiefe CI
Y1  - 2012/06/20
N1  - 10.1001/jama.2012.5287
JO  - JAMA
SP  - 2486
EP  - 2487
VL  - 307
IS  - 23
N2  - 
In Reply: Successful outcomes research using registry data requires formulating clearly stated hypotheses prior to data analysis.1 We examined sex differences in MI symptom presentation (primary objective) and subsequent hospital mortality (secondary objective) after accounting for age among 1.1 million patients enrolled in the National Registry of Myocardial Infarction over the past decade. In our study, chest pain/discomfort was a common symptom of MI seen in more than two-thirds of the overall study population. However, the absence of chest pain/discomfort was more likely in women than in men (42.0% vs 30.7%, respectively). We demonstrated that younger women were more likely to present without chest pain/discomfort and had higher hospital mortality than similarly aged younger men (<55 years of age), but sex differences in presentation and mortality were markedly attenuated and nearly disappeared with increasing age.

SN  - 0098-7484
M3  - doi: 10.1001/jama.2012.5287
UR  - http://dx.doi.org/10.1001/jama.2012.5287
ER  -