TY - JOUR T1 - ACute rhinosinusitis treatment AU - Sun C, Hsu H, Hung S Y1 - 2012/06/13 N1 - 10.1001/jama.2012.4389 JO - JAMA SP - 2368 EP - 2368 VL - 307 IS - 22 N2 - First, the authors state that the inclusion criteria were based on the US Centers for Disease Control and Prevention's expert panel diagnostic criteria for acute bacterial rhinosinusitis.2 The criterion “rhinosinusitis symptoms lasting for less than 7 days that had significantly worsened after initial improvement” was independently considered. However, in the original study by Lindbaek et al,3 this symptom was considered in combination with others to give a specificity of only 0.81 and a sensitivity of 0.66. Thus, selection bias may have occurred, with the enrollment of too many patients with less severe rhinosinusitis. SN - 0098-7484 M3 - doi: 10.1001/jama.2012.4389 UR - http://dx.doi.org/10.1001/jama.2012.4389 ER -