TY  - JOUR
T1  - REversing fragile x
AU  - Hampton T
Y1  - 2012/06/06
N1  - 10.1001/jama.2012.5440
JO  - JAMA
SP  - 2247
EP  - 2247
VL  - 307
IS  - 21
N2  - 
Individuals with FXS have a single mutation in the FMR1 gene that prevents them from producing enough of the fragile X mental retardation protein. This leads to overactivation of a cell signaling pathway involving the metabotropic glutamate receptor 5 (mGlu5).

SN  - 0098-7484
M3  - doi: 10.1001/jama.2012.5440
UR  - http://dx.doi.org/10.1001/jama.2012.5440
ER  -