TY  - JOUR
T1  - COronary heart disease risk factors and mortality—reply
AU  - Canto JG, Kiefe CI, Greenland P
Y1  - 2012/03/21
N1  - 10.1001/jama.2012.325
JO  - JAMA
SP  - 1137
EP  - 1138
VL  - 307
IS  - 11
N2  - 
Dr Santulli seeks additional information that may enhance our study, such as the influence of a dose-dependent effect of CHD risk factors, presence of the metabolic syndrome, other novel risk markers, and infarct size. Unfortunately, these factors were not available in the National Registry of Myocardial Infarction. Although baseline infarct size was not recorded, the finding of an inverse relationship between the number of CHD risk factors and mortality was consistently observed among patients with low-, intermediate-, and high-risk features using 2 well-validated measures of infarct severity (Killip classification and TIMI Risk Index).

SN  - 0098-7484
M3  - doi: 10.1001/jama.2012.325
UR  - http://dx.doi.org/10.1001/jama.2012.325
ER  -