TY - JOUR T1 - EFfects of ect AU - Hampton T Y1 - 2012/05/02 N1 - 10.1001/jama.2012.3723 JO - JAMA SP - 1790 EP - 1790 VL - 307 IS - 17 N2 - Although clinicians have successfully used electroconvulsive therapy (ECT) to treat patients' severe depression for more than 70 years, the mechanisms by which it works remain unclear. Recent research from England suggests that use of electroconvulsive therapy (ECT) to treat patients' severe depression has lasting effects on the functional architecture of a specific region of the brain (Perrin JP et al. Proc Natl Acad Sci U S A. doi:10.1073/pnas.1117206109 [published online March 19, 2012]). SN - 0098-7484 M3 - doi: 10.1001/jama.2012.3723 UR - http://dx.doi.org/10.1001/jama.2012.3723 ER -