TY - JOUR T1 - NEw antiseizure agents AU - Hampton T Y1 - 2012/04/04 N1 - 10.1001/jama.2012.370 JO - JAMA SP - 1357 EP - 1357 VL - 307 IS - 13 N2 - During seizures, T-type calcium channels become active and stimulate neurons to fire at a high frequency. The new compounds, called Z941 and Z944, preferentially blocked channels responsible for high-frequency neuron firing. SN - 0098-7484 M3 - doi: 10.1001/jama.2012.370 UR - http://dx.doi.org/10.1001/jama.2012.370 ER -