TY - JOUR T1 - USe of administrative data to estimate the incidence of statin-related rhabdomyolysis AU - Floyd JS, Heckbert SR, Weiss NS, Carrell DS, Psaty BM Y1 - 2012/04/18 N1 - 10.1001/jama.2012.489 JO - JAMA SP - 1580 EP - 1582 VL - 307 IS - 15 N2 - To the Editor: Studies of rare adverse drug reactions (ADRs) are difficult because they require large numbers of exposed persons to identify an adequate number of cases. Spontaneous adverse events reports have been used to identify cases of rhabdomyolysis, a rare but serious complication of statin use.1 A complex algorithm based on administrative data also has been used to identify cases of rhabdomyolysis and myopathy among enrollees of several large health plans.2- 3 We conducted this population-based epidemiological study to evaluate use of the diagnostic code for rhabdomyolysis introduced in 2006 as a method of estimating the incidence of statin-related rhabdomyolysis and myopathy. SN - 0098-7484 M3 - doi: 10.1001/jama.2012.489 UR - http://dx.doi.org/10.1001/jama.2012.489 ER -