TY  - JOUR
T1  - PRomising leishmaniasis drug
AU  - Friedrich MJ
Y1  - 2012/03/21
N1  - 10.1001/jama.2012.295
JO  - JAMA
SP  - 1129
EP  - 1129
VL  - 307
IS  - 11
N2  - 
Fexinidazole has been found safe in early clinical trials for African sleeping sickness, a disease caused by the parasite Trypanosoma brucei. Because visceral leishmaniasis is caused by a closely related protozoan parasite, Leishmania donovani, and current treatments for visceral leishmaniasis are less than ideal, scientists tested fexinidazole against leishmaniasis. They gave a daily oral dose of the compound for 5 days to leishmaniasis-infected mice and observed almost complete suppression of infection.

SN  - 0098-7484
M3  - doi: 10.1001/jama.2012.295
UR  - http://dx.doi.org/10.1001/jama.2012.295
ER  -