TY - JOUR T1 - UNique food preservation Y1 - 2012/02/08 N1 - 10.1001/jama.2012.35 JO - JAMA SP - 545 EP - 545 VL - 307 IS - 6 N2 - Bearing in mind the familiar fact that certain substances which are not readily oxidized or destroyed in the body may reappear in the secretions, such as milk, and in the eggs of animals, he has attempted to ascertain whether compounds exhibiting a preservative action are eliminated in this manner. Physiologically this question is of interest in relation to the permeability of the ovarian egg-membranes and the passage of substances from the blood through both follicular and vitelline membranes. The transportation of the fat-soluble dye Sudan III into the yolk of the hen's egg can easily be demonstrated, the coloring-matter appearing as rings of pink in a cross-section of the egg of a hen which has received the dye. Such pigments, insoluble in water, travel dissolved in fat in the organism, being deposited with it in characteristic locations such as adipose tissue or egg yolk, or being excreted with the fat of milk or dissolved in the special solvents of the bile.1 In other words, compounds which are comparatively inert and not destroyed in the body may tend to find a suitable solvent and thus travel from place to place until eliminated in some way. SN - 0098-7484 M3 - doi: 10.1001/jama.2012.35 UR - http://dx.doi.org/10.1001/jama.2012.35 ER -