TY - JOUR T1 - PRostate cancer screening—the evidence, the recommendations, and the clinical implications AU - Chou R, LeFevre ML Y1 - 2011/12/28 N1 - 10.1001/jama.2011.1891 JO - JAMA SP - 2721 EP - 2722 VL - 306 IS - 24 N2 - The mission of the USPSTF is to improve the health of all persons in the United States by making evidence-based recommendations about clinical preventive services. Each USPSTF recommendation is based on a systematic review of the evidence.1 Before making a recommendation about a preventive service, the task force requires that the evidence be sufficient to estimate with at least moderate certainty the balance of benefits relative to harms.2 In this case, across the population of screened men, the USPSTF determined that benefits of prostate-specific antigen (PSA)–based screening for prostate cancer were outweighed by harms. SN - 0098-7484 M3 - doi: 10.1001/jama.2011.1891 UR - http://dx.doi.org/10.1001/jama.2011.1891 ER -