TY  - JOUR
T1  - BLocking cancer-induced epilepsy
AU  - Hampton T
Y1  - 2011/11/02
N1  - 10.1001/jama.2011.1575
JO  - JAMA
SP  - 1853
EP  - 1853
VL  - 306
IS  - 17
N2  - 
Immunodeficient mice implanted with human-derived glioma cells developed spontaneous and recurring abnormal brain activity; brain slices from these mice showed marked glutamate release from the tumor. When the researchers inhibited glutamate release from tumors with sulfasalazine at concentrations equivalent to those used to treat Crohn disease in humans, the mice had fewer epileptic events.

SN  - 0098-7484
M3  - doi: 10.1001/jama.2011.1575
UR  - http://dx.doi.org/10.1001/jama.2011.1575
ER  -