TY  - JOUR
T1  - NEw model system offers clues to als
AU  - Kuehn BM
Y1  - 2011/10/12
N1  - 10.1001/jama.2011.1439
JO  - JAMA
SP  - 1534
EP  - 1534
VL  - 306
IS  - 14
N2  - 
ALS is a progressive and ultimately fatal disorder in which the motor neurons in a patient's central nervous system die off, causing paralysis and eventually respiratory failure. Most cases are sporadic, but about 20% are linked to mutations in the superoxide dismutase 1 (SOD1) gene. However, scientists have so far been unable to identify the precise mechanisms behind the motor neuron loss.

SN  - 0098-7484
M3  - doi: 10.1001/jama.2011.1439
UR  - http://dx.doi.org/10.1001/jama.2011.1439
ER  -