TY - JOUR T1 - CHallenges facing the us patient-centered outcomes research institute AU - Ommaya AK, Kupersmith J Y1 - 2011/08/17 N1 - 10.1001/jama.2011.1171 JO - JAMA SP - 756 EP - 757 VL - 306 IS - 7 N2 - Realizing the promise of comparative effectiveness research and achieving health care practice change require not only identifying research priorities, but also determining how to conduct the studies and implement the results. The new Patient-Centered Outcomes Research Institute (PCORI) is a nonprofit entity charged with prioritizing and supporting studies and improvement in the methods of comparative effectiveness research.1 By 2014, the PCORI budget may increase to more than $500 million. It is funded by Medicare, private health insurers, and self-insured plans. SN - 0098-7484 M3 - doi: 10.1001/jama.2011.1171 UR - http://dx.doi.org/10.1001/jama.2011.1171 ER -