TY  - JOUR
T1  - SPontaneous and sporadic trypsinogen mutations in idiopathic pancreatitis
AU  - Simon P, Weiss F, Zimmer K, et al
Y1  - 2002/11/06
N1  - 10.1001/jama.288.17.2118
JO  - JAMA
SP  - 2122
EP  - 2122
VL  - 288
IS  - 17
N2  - 
To the Editor: Hereditary pancreatitis is an
uncommon variety of pancreatitis. It generally follows an autosomal dominant
inheritance and is associated with germline mutations in the cationic trypsinogen
(PRSS1) gene.1 Thus,
genetic testing is often recommended when 2 or more family members are diagnosed
with idiopathic pancreatitis. However, the prevalence of trypsinogen mutations
among patients with idiopathic pancreatitis and without a family history remains
unknown.

SN  - 0098-7484
M3  - doi: 10.1001/jama.288.17.2118
UR  - http://dx.doi.org/10.1001/jama.288.17.2118
ER  -