TY - JOUR T1 - TReatment of congestive heart failure AU - de Denus S, Spinler SA Y1 - 2002/05/01 N1 - 10.1001/jama.287.17.2209 JO - JAMA SP - 2209 EP - 2210 VL - 287 IS - 17 N2 - To the Editor: In their Scientific Review article about the management of advanced heart failure, Dr Nohria and colleagues1 suggested that angiotensin II receptor blockers (ARBs) are a reasonable alternative for patients who cannot tolerate angiotensin converting enzyme (ACE) inhibitors because of severe cough or angioedema. Although we agree that ARBs, or a combination of hydralazine and a nitrate, constitute a reasonable alternative in patients experiencing persistent cough associated with receiving ACE inhibitors, we believe that ARBs in patients with a history of an ACE inhibitor–associated angioedema should only be used with extreme caution, if at all. SN - 0098-7484 M3 - doi: 10.1001/jama.287.17.2209 UR - http://dx.doi.org/10.1001/jama.287.17.2209 ER -