TY - JOUR T1 - HOw often should patients with diabetes be screened for retinopathy?—reply AU - Fontanarosa PB, Vijan S, Hofer TP, Hayward RA Y1 - 2000/07/26 N1 - 10.1001/jama.284.4.436 JO - JAMA SP - 437 EP - 439 VL - 284 IS - 4 N2 - We are perplexed by Dr Javitt's criticism of our blindness utility measure, since our base model used the same utility value (0.69) that he and his colleagues used in their most recent model.1- 2 However, we agree that estimates of utility of visual impairment vary substantially, and Dr Brown and colleagues cite interesting recent articles on this topic. Still, although lower utility measures would influence the estimates, especially for high-risk patients (whom we already agree should be screened annually), no assumptions in our sensitivity analyses had a major effect on the cost-effectiveness for low-risk patients, even if we set the utility value to 0. In contrast, the inclusion of any degree of dislike of retinal examination (such as a disutility value of 0.0014, reflecting one half day lost per year) makes annual screening very unfavorable for most patients. The important result of our study is the stable and robust finding of minimal benefit of annual vs every 2- to 3-year screening for low-risk individuals, not conclusions about average cost-effectiveness for the overall population. None of the concerns raised in the letters change this conclusion. SN - 0098-7484 M3 - doi: 10.1001/jama.284.4.436 UR - http://dx.doi.org/10.1001/jama.284.4.436 ER -