TY - JOUR T1 - ANtibiotic use and risk of myocardial infarction—reply AU - Meier CR, Derby LE, Jick SS, Vasilakis C, Jick H Y1 - 1999/12/01 N1 - 10-1001/pubs.JAMA-ISSN-0098-7484-282-21-jbk1201 JO - JAMA SP - 1997 EP - 1999 VL - 282 IS - 21 N2 - In Reply: Dr Haider and colleagues state that residual confounding, chance, or bias may be alternative explanations for our findings. We agree, as discussed in detail in our article. However, 3 reasons speak against selection bias (ie, antibiotic users differ from nonusers with regard to cardiovascular risk factors and medical attention sought): (1) there were no subjects with diagnosed cardiovascular diseases in our study; (2) we adjusted the analysis for number of practice visits (and therefore for medical attention sought) with no effect on the results; and (3) we analyzed antibiotic use in groups and not just users vs nonusers, which would mean that any bias had to selectively affect users of certain antibiotics but not others. SN - 0098-7484 M3 - doi: 10-1001/pubs.JAMA-ISSN-0098-7484-282-21-jbk1201 UR - http://dx.doi.org/10-1001/pubs.JAMA-ISSN-0098-7484-282-21-jbk1201 ER -