TY  - JOUR
T1  - TOtal parenteral nutrition for critically ill patients
AU  - Khaodhiar L, Bistrian BR
Y1  - 1999/10/20
N1  - 10-1001/pubs.JAMA-ISSN-0098-7484-282-15-jac90009
JO  - JAMA
SP  - 1423
EP  - 1425
VL  - 282
IS  - 15
N2  - 
To the Editor: The meta-analysis of total parenteral
nutrition (TPN) in the critically ill patient by Dr Heyland and colleagues1 illustrates several of the serious problems of
meta-analysis compared with randomized clinical trials. These involve heterogeneity
of the trials included, failure of the investigators performing the meta-analysis
to understand the basic issues, and defects in abstracting.2
Several problems illustrate why there should be a reluctance to base clinical
decisions about the use of TPN on the distilled findings from this meta-analysis.

SN  - 0098-7484
M3  - doi: 10-1001/pubs.JAMA-ISSN-0098-7484-282-15-jac90009
UR  - http://dx.doi.org/10-1001/pubs.JAMA-ISSN-0098-7484-282-15-jac90009
ER  -