TY - JOUR T1 - SHould benzodiazepines in an 87-year-old woman be tapered and discontinued? AU - Portnoi VA Y1 - 1999/09/22 N1 - 10.1001/jama.282.12.1128 JO - JAMA SP - 1128 EP - 1128 VL - 282 IS - 12 N2 - To the Editor: A recent Clinical Crossroads1 presented an 87-year-old woman taking a benzodiazepine for at least 15 years in addition to diphenhydramine hydrochloride as needed. Dr Salzman suggested that the patient continue with this regimen because he believed the patient experienced a continuous therapeutic effect. Salzman acknowledged the detrimental effect of benzodiazepines on short- and long-term memory in the elderly, but dismissed it based on data from his unpublished findings that many patients accept the loss of "sharp memory" for a "day that calms." SN - 0098-7484 M3 - doi: 10.1001/jama.282.12.1128 UR - http://dx.doi.org/10.1001/jama.282.12.1128 ER -