TY - JOUR T1 - CHinese herbal medicine for irritable bowel syndrome—reply AU - Bensoussan A, Talley NJ, Menzies R Y1 - 1999/09/15 N1 - 10-1001/pubs.JAMA-ISSN-0098-7484-282-11-jac90008 JO - JAMA SP - 1035 EP - 1037 VL - 282 IS - 11 N2 - The standard formula was devised through the study and collaboration of 2 principal Chinese herbalists. While contained within it are parts of classic formulations, it does not strictly follow previous prescriptions. The placebo was prepared by a pharmaceutical contractor with previous experience in this area. It contained 78.2% calcium hydrogen phosphate, 19.6% soy fiber, 0.3% cosmetic brown, 0.5% cosmetic yellow, 0.01% edicol blue, 0.09% identical licorice dry flavor, and 0.3% bitter flavor. We are reasonably confident that the placebo was completely inert. Patients who received the placebo responded in a predictable fashion overall. The gram proportions of herbal ingredients in the standard formula were converted to the nearest 0.5%. SN - 0098-7484 M3 - doi: 10-1001/pubs.JAMA-ISSN-0098-7484-282-11-jac90008 UR - http://dx.doi.org/10-1001/pubs.JAMA-ISSN-0098-7484-282-11-jac90008 ER -