TY - JOUR T1 - DIuretics for hypertension—reply AU - Moser M Y1 - 1999/08/11 N1 - 10-1001/pubs.JAMA-ISSN-0098-7484-282-6-jbk0811 JO - JAMA SP - 523 EP - 525 VL - 282 IS - 6 N2 - In Reply: Dr Messerli and colleagues are correct in pointing out that their study was short-term. In 1991, we reviewed data on the differing opinions regarding the effects of diuretics on LVH and concluded that LVH regression occurred if blood pressure was lowered.1 The recent meta-analysis, which noted that ACE inhibitors were the most effective agents in causing regression, included several studies that were short-term and enrolled limited numbers of subjects. The conclusion may be correct, but one cannot dismiss data from the Treatment of Mild Hypertension Study and the Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents study, both of which showed that diuretics were as effective or more effective than other medications. SN - 0098-7484 M3 - doi: 10-1001/pubs.JAMA-ISSN-0098-7484-282-6-jbk0811 UR - http://dx.doi.org/10-1001/pubs.JAMA-ISSN-0098-7484-282-6-jbk0811 ER -