TY - JOUR T1 - DEbate continues on use of psa testing for early detection of prostate cancer AU - Friedrich MJ Y1 - 2011/06/08 N1 - 10.1001/jama.2011.777 JO - JAMA SP - 2273 EP - 2276 VL - 305 IS - 22 N2 - Prostate cancer appears in a large percentage of men as they age, but is indolent most of the time. Critics emphasize that PSA testing is an imperfect screening tool because it does not differentiate clinically significant tumors from ones that would never cause harm, and the result is overdiagnosis and overtreatment. Others defend the use of PSA testing and say that a more rational, evidence-based approach to using it can help detect and treat prostate cancer early in men who would die of the disease. SN - 0098-7484 M3 - doi: 10.1001/jama.2011.777 UR - http://dx.doi.org/10.1001/jama.2011.777 ER -