TY - JOUR T1 - STroke after coronary artery bypass graft surgery—reply AU - Sabik JF, Blackstone EH Y1 - 2011/06/01 N1 - 10.1001/jama.2011.708 JO - JAMA SP - 2171 EP - 2172 VL - 305 IS - 21 N2 - In Reply: As Dr Fan and colleagues discuss, and we stated as a limitation of our study, we did not report whether the perioperative strokes were due to embolism, thrombosis, hemorrhage, or hypoperfusion. These data are not routinely captured in our prospective database and therefore would require considerable work to obtain. However, from what is known about stroke and coronary surgery, the majority are due to embolism, most likely from manipulation of an atherosclerotic ascending aorta.1 Our findings support this in that stroke increased directly with the number of atherosclerotic risk factors and was lowest for patients with minimal manipulation of the aorta. SN - 0098-7484 M3 - doi: 10.1001/jama.2011.708 UR - http://dx.doi.org/10.1001/jama.2011.708 ER -