RT Journal
A1 Herr HW
T1 INtravesical bacille calmette-guérin in patients with asymptomatic bacteriuria
JF JAMA
JO JAMA
YR 2011
FD April 13
VO 305
IS 14
SP 1413
OP 1414
DO 10.1001/jama.2011.428
UL http://dx.doi.org/10.1001/jama.2011.428
AB 
To the Editor: Asymptomatic bacteriuria is common in adults and does not require treatment.1 Practice guidelines, however, recommend antibiotics to sterilize the urine before urological procedures.2 Although intravesical bacille Calmette-Guérin (BCG) therapy for high-risk superficial bladder cancer is not specifically mentioned, urologists are reluctant to administer BCG to infected patients because of a possible risk of bacterial or BCG sepsis or an abrogated response to BCG.3 On the other hand, antibacterial treatment of asymptomatic bacteriuria leads to treatment delay and promotes antibiotic resistance. This study investigated whether intravesical BCG is safe and effective in bladder cancer patients with asymptomatic bacteriuria.