RT Journal
A1 Hughes JM
T1 PReserving the lifesaving power of antimicrobial agents
JF JAMA
JO JAMA
YR 2011
FD March 9
VO 305
IS 10
SP 1027
OP 1028
DO 10.1001/jama.2011.279
UL http://dx.doi.org/10.1001/jama.2011.279
AB 
Among the most important medicines ever discovered, antimicrobial agents have saved millions of lives and improved the outcomes for countless patients since these drugs were introduced in the early 1930s. However, the effectiveness of these lifesaving resources is at risk. Many medical advances that physicians and patients take for granted—including cancer treatment, surgery, transplantation, and neonatal care—are endangered by increasing antibiotic resistance and a distressing decline in the antibiotic research and development pipeline.1