RT Journal A1 Annema JT, Rintoul RC, Tournoy KG T1 MEdiastinal staging procedures in non–small cell lung cancer—reply JF JAMA JO JAMA YR 2011 FD March 2 VO 305 IS 9 SP 890 OP 891 DO 10.1001/jama.2011.225 UL http://dx.doi.org/10.1001/jama.2011.225 AB First, they argue that the cost of endosonography equipment and consumables may be an obstacle that limits availability. Although we acknowledge that these direct costs are an issue, more relevant is the cost-effectiveness of endosonography in relation to surgical staging techniques. In a decision tree sensitivity analysis, EBUS-TBNA has been shown to have lower cost in comparison with mediastinoscopy.1 Cost utility and health economic analyses from our trial are now being performed, which will provide further insights.