RT Journal
A1 Hampton T
T1 HEart condition model
JF JAMA
JO JAMA
YR 2011
FD March 2
VO 305
IS 9
SP 876
OP 876
DO 10.1001/jama.2011.215
UL http://dx.doi.org/10.1001/jama.2011.215
AB 
Scientists have used cells from a patient with long QT syndrome to develop a new stem cell model of this life-threatening heart condition, which features abnormal ion channel function (Itzhaki I et al. Nature. doi: 10.1038/nature09747 [published online ahead of print January 16, 2011]). The researchers, from the Israel Institute of Technology in Haifa, generated induced pluripotent stem cells from the patient's fibroblasts and coaxed them to become cardiac muscle cells displaying abnormal electrical activity typical of the syndrome.