RT Journal
A1 Kuehn BM
T1 BUprenorphine during pregnancy
JF JAMA
JO JAMA
YR 2011
FD January 26
VO 305
IS 4
SP 348
OP 348
DO 10.1001/jama.2010.1965
UL http://dx.doi.org/10.1001/jama.2010.1965
AB 
Although methadone treatment is the current standard of care for pregnant women with opioid addiction, some studies have suggested buprenorphine might offer additional benefits to the infants of treated mothers. In the current study, 175 women at 8 sites were randomly assigned to receive either buprenorphine or methadone for opioid addiction. Infants in the buprenorphine group required less morphine to treat neonatal abstinence syndrome than those in the methadone group (mean dose: 1.1 mg vs 10.4 mg), required fewer days of treatment (4.1 days vs 9.9 days), and had shorter hospital stays (10.0 vs 17.5 days).