RT Journal
T1 LAndry's paralysis.
JF Journal of the American Medical Association
JO Journal of the American Medical Association
YR 1899
FD July 15
VO XXXIII
IS 3
SP 169
OP 170
DO 10.1001/jama.1899.02450550053017
UL http://dx.doi.org/10.1001/jama.1899.02450550053017
AB While the precise nature of the disorder first described by Landry, and hence known by his name, remains unknown, there seems good reason for believing that the symptomatic manifestations of the affection are dependent on deranged functional activity of the peripheral motor neuron. Going a step further, it may readily be conceived that the disturbance of function is due to the activity of toxic substances introduced from without or generated within the body as a result of the vital activity of micro-organisms or of derangement in the bodily metabolism. However this may be, in some cases the symptoms have been indicative of peripheral neuritis, in others of anterior poliomyelitis. Of the infectious nature of the disease the presence of constitutional symptoms of greater or less gravity may be accepted as evidence. Symptoms of the affection consist in gradually progressive and extending motor paralysis of flaccid type, with loss of reflexes,