RT Journal T1 AUto-infection from the products of gastro-intestinal fermentation. JF Journal of the American Medical Association JO Journal of the American Medical Association YR 1889 FD September 21 VO XIII IS 12 SP 419 OP 420 DO 10.1001/jama.1889.02401090023005 UL http://dx.doi.org/10.1001/jama.1889.02401090023005 AB There is a large and important class of cases, examples of which are constantly coming under the observation of the general practitioner, sometimes under one guise, sometimes under another; at times bearing clinical aspects of familiar appearance, again presenting an array of symptoms without apparent interdependence and exhibiting manifold functional disorders which seem to affect every organ of the human economy, and to spring from sources so well hidden as to baffle the quest of even the astute physician. These are the cases of that hydra-headed enemy of modern civilization, Indigestion. To compass etiology we are obliged to summon to our aid all the wisdom of physiology, chemistry and bacteriology. In our efforts at treatment we have already well-nigh exhausted the resources of materia medica and dietetics, and have little to fall back upon save hygiene—id est, common sense.We can scarcely doubt—indeed, we have already admitted—that it is