RT Journal T1 THe biologic standardization of digitalis JF Journal of the American Medical Association JO Journal of the American Medical Association YR 1909 FD June 12 VO LII IS 24 SP 1931 OP 1931 DO 10.1001/jama.1909.02540500033008 UL http://dx.doi.org/10.1001/jama.1909.02540500033008 AB We publish elsewhere1 in this issue an abstract of Bulletin No. 48 of the Hygienic Laboratory, Washington, D. C., entitled "The Physiological Standardization of Digitalis." It contains a good deal of material which is of great interest to the physician, because, in addition to giving a complete historical review of the various steps which have led up to biologic standardization of drugs, and an investigation into the accuracy of these methods, it also gives the results of the writers' examination of some of the proprietary preparations of digitalis which are on the market. Three of these nonpharmacopeial preparations compared very favorably with the official fluidextracts as the results given in the table on page 1939 show. With two more preparations, however, the findings were not as favorable, and they furnish examples of the vast difference between theory and fact, or perhaps it might be said between manufacturers' claims and