RT Journal
A1 Power H
T1 SErum sickness
JF Journal of the American Medical Association
JO Journal of the American Medical Association
YR 1909
FD May 8
VO LII
IS 19
SP 1514
OP 1515
DO 10.1001/jama.1909.02540450046013
UL http://dx.doi.org/10.1001/jama.1909.02540450046013
AB To the Editor: 
    —The increasing interest in serum poisoning, as shown by the recent report of cases, leads me to relate the following personal experience. I am furthermore induced to do so by the possibility herein shown of the sensitive condition far exceeding the usual time limits.In 1902, I attended a case of diphtheria. I took an immunizing injection of antitoxin of 1,000 units. No inconvenience or rash followed. A few months later my duties brought me into close relation with bubonic plague and I was injected with Haffkine's prophylactic. This is a vaccine. A very severe reaction followed, temperature rose to 102 F., there was much urticaria and general malaise for two days. I looked on this as a toxic and not a serum reaction. In January of this year I was in very close relation to an unusually severe case of diphtheria, in which I administered 108,000