RT Journal A1 Neer CS T1 PRophylactic effect of antitoxin on the child in utero JF Journal of the American Medical Association JO Journal of the American Medical Association YR 1909 FD February 27 VO LII IS 9 SP 717 OP 717 DO 10.1001/jama.1909.02540350043015 UL http://dx.doi.org/10.1001/jama.1909.02540350043015 AB To the Editor:  —In connection with the report by Dr. Ransom, the following may be of interest:J. C., male, colored, contracted smallpox, the characteristic eruption appearing Dec. 31, 1908, three days after the onset of the usual initial symptoms. His family consisted of a 3-year-old son and the wife, who was pregnant at term. The wife and child were at once successfully vaccinated and did not contract smallpox. The woman was delivered Jan. 11, 1909, eleven days after the appearance of the eruption in the husband, who, at this time still had a few crusts. The parents refused to have the baby vaccinated, but it did not contract the disease, although no precautions were taken to prevent contact with the father; the entire family lived principally in one room.There can be no doubt about the identity of the disease, as the symptoms and eruption were typical, and other