RT Journal A1 Tilkian SM T1 DEpendence on cyanocobalamin injections JF JAMA JO JAMA YR 1989 FD September 15 VO 262 IS 11 SP 1468 OP 1469 DO 10.1001/jama.1989.03430110058016 UL http://dx.doi.org/10.1001/jama.1989.03430110058016 AB To the Editor. —  I started reading the article by Drs Lawhorne and Ringdahl1 with interest. By the time I finished, I was angry and depressed enough to write this letter. Throughout the article, there was no mention of how vitamin B12 deficiency can be scientifically assessed for clinical purposes.Current practice seems to emphasize the art of medicine, and also the economics of medicine under the guise of cost containment, at the expense of science. The workup of a patient with vitamin B12 problems can be expensive and inconclusive, but it can also be objective and scientific with minimum cost.2 One does not have to do Schilling or deoxyuridine suppression tests, measure vitamin B12 levels, perform gastrointestinal series, etc, which are expensive and sometimes uninformative. There are simple tests that every physician orders routinely but perhaps does not look at critically.For example, the