RT Journal A1 Borland CR, Farrar WE T1 REversible neutropenia from vancomycin JF JAMA JO JAMA YR 1979 FD November 30 VO 242 IS 22 SP 2392 OP 2393 DO 10.1001/jama.1979.03300220012007 UL http://dx.doi.org/10.1001/jama.1979.03300220012007 AB To the Editor.—  Although ototoxicity and nephrotoxicity are the most feared complications associated with vancomycin hydrochloride,1 at least seven patients in whom neutropenia developed have been described in the literature (236:1604, 1976).2-4 Three additional cases have been reported to the Eli Lilly Company (Dr A. F. Crumley, written communication,Penicillin Gand Gentamicin Sulfate Erythromycin and Rifampin 20,000 — 10,000 — Vancomycin Hydrochloride Total WBC Count —Neutrophil Count 10 20 30 40 50 Day of Hospitalization 60 70 80 90 Total WBC and neutrophil counts during hospitalization. 1978). In most of the well-documented cases, the patient was receiving or had recently received other agents that might have caused the neutropenia. We have recently seen a patient whose severe