RT Journal
A1 Naqvi SH, Dunkle LM, Timmerman KJ, Reichley RM, Stanley DL, O'Connor D
T1 ANtibiotic usage in a pediatric medical center
JF JAMA
JO JAMA
YR 1979
FD November 2
VO 242
IS 18
SP 1981
OP 1984
DO 10.1001/jama.1979.03300180025025
UL http://dx.doi.org/10.1001/jama.1979.03300180025025
AB Antibiotic usage in a large pediatric teaching hospital was evaluated during a three-month period. A total of 1,067 patients received antibiotics and 295 patient records were reviewed. One hundred sixty-nine courses of antibiotics were administered to surgical patients, 77% for surgical prophylaxis. One hundred forty-seven antibiotic courses administered to medical patients were therapeutic in 61.2% and in 35.3% were given because of suspicion of infection. Ampicillin was the most commonly used antibiotic; cephalosporins were used for surgical prophylaxis. Aminoglycosides were used commonly for suspected infection in medical patients. Antibiotic management was inappropriate in 66% of surgical patients and in 21% of medical patients. Not obtaining appropriate studies prior to and during therapy were common infractions on all services. Surgical prophylaxis was frequently inappropriate by reason of no indication, wrong drug or dose, or inappropriate timing.(JAMA 242:1981-1984, 1979)