RT Journal
A1 Barrett-Connor E, Brown W, Turner J, Austin M, Criqui MH
T1 HEart disease risk factors and hormone use in postmenopausal women
JF JAMA
JO JAMA
YR 1979
FD May 18
VO 241
IS 20
SP 2167
OP 2169
DO 10.1001/jama.1979.03290460031015
UL http://dx.doi.org/10.1001/jama.1979.03290460031015
AB A population of 1,496 women aged 55 to 74 years was studied for the distribution of heart disease risk factors in the presence or absence of postmenopausal estrogens. Current hormone use was reported by 39%. Hormone users were significantly slimmer than nonusers at all ages. After adjustment for the effect of obesity, hormone users had significantly lower mean levels of plasma cholesterol and higher mean levels of plasma triglycerides than nonusers. Blood pressure and fasting plasma glucose concentration tended to be lower among hormone users, although the differences were not statistically significant in all age groups. This article discusses the theoretical implications of these observations for cardiovascular disease mortality and contrasts them with the cancer risk of postmenopausal estrogen use.(JAMA 241:2167-2169, 1979)