RT Journal A1 Lyon LJ, Nevins MA T1 CArcinoma of the colon presenting as pyogenic arthritis JF JAMA JO JAMA YR 1979 FD May 11 VO 241 IS 19 SP 2060 OP 2060 DO 10.1001/jama.1979.03290450058026 UL http://dx.doi.org/10.1001/jama.1979.03290450058026 AB BACTERIAL endocarditis caused by enteric organisms such as Streptococcus bovis may be the initial manifestation of occult colonic neoplasm.1 Like bacterial endocarditis, pyogenic arthritis frequently results from bacteremia. A patient who had pyogenic arthritis caused by another intestinal organism, group G Streptococcus, ultimately proved to have carcinoma of the colon.Report of a Case  A 53-year-old woman who had been in good health except for obesity and chronic osteoarthritis of the left knee had acute pain and swelling of the left knee. When culture of the joint aspirate grew β-hemolytic Streptococcus, later identified as belonging to Lancefield group G, she was hospitalized for further examination and therapy. The patient denied all gastrointestinal symptoms.On physical examination she was afebrile. There were no abnormalities except for obesity and signs of acute inflammation of the left knee. Blood cultures were negative. The patient received 20 million units of intravenous, aqueous penicillin