RT Journal
A1 Lemere F
T1 CHlorpromazine for treatment of underweight
JF JAMA
JO JAMA
YR 1969
FD December 8
VO 210
IS 10
SP 1923
OP 1923
DO 10.1001/jama.1969.03160360069023
UL http://dx.doi.org/10.1001/jama.1969.03160360069023
AB To the Editor:— 
    The response to the question regarding management of the underweight woman which appeared in The Journal (209:2061, 1969) suggested insulin injections and large doses of chlorpromazine but only for inpatients. For outpatients, the only suggestion was reassurance that underweight was healthy and cosmetically advantageous. I would doubt that severe underweight is cosmetically acceptable to most people. At any rate, many patients who wish to gain weight can often achieve this through the use of chlorpromazine on an office or outpatient basis. One of the side effects, often undesirable, of the psychiatric use of phenothiazines, especially chlorpromazine, is a marked gain in weight. Weight gain can be controlled by the dosage which should be to the point of comfortable tolerance, such as 75 to 150 mg daily. On this regimen, if followed for two or three months, weight gain can usually be achieved, although it often seems